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Endocrine Disruption

Bisphenol A

Bisphenol A and Human Health

In September, 2013, TEDX's manuscript Bisphenol A and Human Health: A Review of the Literature was published in the peer-reviewed scientific journal Reproductive Toxicology. This review confirms that BPA can be harmful to humans at levels experienced by the general population, and well below levels considered safe by the EPA. 


Link to the publisher:

Bisphenol A and Human Health: A Review of the Literature.

There is growing evidence that bisphenol A (BPA) may adversely affect humans. BPA is an endocrine disruptor that has been shown to be harmful in laboratory animal studies. Until recently, there were relatively few epidemiological studies examining the relationship between BPA and health effects in humans. However, in the last year, the number of these studies has more than doubled. A comprehensive literature search found 91 studies linking BPA to human health; 53 published within the last year. This review outlines this body of literature, showing associations between BPA exposure and adverse perinatal, childhood, and adult health outcomes, including reproductive and developmental effects, metabolic disease, and other health effects. These studies encompass both prenatal and postnatal exposures, and include several study designs and population types. While it is difficult to make causal links with epidemiological studies, the growing human literature correlating environmental BPA exposure to adverse effects in humans, along with laboratory studies in many species including primates, provides increasing support that environmental BPA exposure can be harmful to humans, especially in regards to behavioral and other effects in children.

Download the article

Click here to download a pdf of the accepted manuscript. For a summary table of the results click here.


Rochester JR, Bisphenol A and Human Health: A review of the literature. Reproductive Toxicology. 2013 42C:132-155.