Endocrine Disruption

Bisphenol A

ANALYSES FOR LOW-DOSE bPA SPREADSHEETS

Outcome Analysis
June, 2009

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The following provides an analysis of each outcome in the Low Dose Bisphenol A Spreadsheet.   The results are grouped into the following categories:  Male Reproductive System Outcomes, Female Reproductive System Outcomes, Miscellaneous Outcomes, Early Offspring Outcomes, Brain/Behavior Outcomes, and Organ/System Outcomes.   The total number of studies in each endpoint is reported, as well as the number of studies that demonstrated results, and the number of studies that did not.  Percentages of each are also provided.  The specific changes found are outlined below each of the tables.  For a broader view of the data, please refer to the summary and charts.

Mammalian Outcome Analyses
June, 2009

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These analyses examine only those studies that used mammals in their design (rats and mice, primarily).  The mammalian studies are further grouped by timing of exposure and broken out into the main endpoints found in the spreadsheet.  Data are summarized in tables with specific results listed below each table.

Non-Mammalian Outcome Analyses
June, 2009

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Studies that used any species other than mammals are summarized in these analyses.  These studies are grouped by timing of exposure and broken out into the main endpoints found in the spreadsheet.  Data are summarized in tables with specific results listed below each table.

In-Vitro Outcome Analyses
June, 2009

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Studies utilizing in-vitro methods and any type of tissue or cell are summarized in these analyses.  They are grouped into the same endpoints as found in the main spreadsheet with the data summarized in tables and specific information on the results listed below each table.