The weeks shown in color represent the start and end points of chemical exposure for each study.

Study Results Study Details References

Results for Phthalates (DBP)

Decreased frequency of grooming at 0.01 mg/kg

Subjects: Sprague-Dawley rats

Chemical: Phthalates (DBP)

Low doses tested: 0.01 or 1.0 mg/kg bw/d

Route of administration: dissolved in sesame oil and delivered in feed

Exposure duration: gestational day 8 – gestational day 22 (comparable to human prenatal development from approximately day 1 of week 2 to day 1 of week 18)

Age of measurement: birth through 4 weeks of age

Reference [PubMed Link]
Hoshi H, Ohtsuka T. 2009. Adult Rats Exposed to Low-Doses of Di-n-Butyl Phthalate During Gestation Exhibit Decreased Grooming Behavior. Bull Environ Contam Toxicol 83(1):62-66.