The weeks shown in color represent the start and end points of chemical exposure for each study.

Study Results Study Details References

Results for Chlorpyrifos

Decreased frequency of self grooming; increased frequency of aggressive grooming among males

Subjects: CD-1 mice

Chemical: Chlorpyrifos

Low doses tested: 1.0 or 3.0 mg/kg bw/d

Route of administration: dissolved in DMSO and injected sub-cutaneously

Exposure duration: post-natal day 1 – post-natal day 4 (comparable to human prenatal development from approximately day 1 of week 15 to day 1 of week 21)

Age of measurement: through adulthood

Reference [PubMed Link]
Ricceri L, Markina N, Valanzano A, Fortuna S, Cometa MF, Meneguz A, Calamandrei G. 2003. Developmental exposure to chlorpyrifos alters reactivity to environmental and social cues in adolescent mice. Toxicology & Applied Pharmacology 191(3):189-201.
Study Results Study Details References

Results for Chlorpyrifos

Decreased total and soluble AchE activity at 4 days of age but not later; decreased soluble AchE G4 molecular form

Subjects: CD-1 mice

Chemical: Chlorpyrifos

Low doses tested: 1.0 or 3.0 mg/kg bw/d

Route of administration: dissolved in DMSO and injected sub-cutaneously

Exposure duration: post-natal day 1 – post-natal day 4 (comparable to human prenatal development from approximately day 1 of week 15 to day 1 of week 21)

Age of measurement: through adulthood

Reference [PubMed Link]
Ricceri L, Markina N, Valanzano A, Fortuna S, Cometa MF, Meneguz A, Calamandrei G. 2003. Developmental exposure to chlorpyrifos alters reactivity to environmental and social cues in adolescent mice. Toxicology & Applied Pharmacology 191(3):189-201.