The weeks shown in color represent the start and end points of chemical exposure for each study.

Study Results Study Details References

Results for Bisphenol A

Increased incidence of cystic endometrial hyperplasia at 100 μg/kg; also evidence (non-significant) of progressive proliferative lesions, leiomyomas and stromal polyps in all treated groups

Subjects: CD-1 mice

Chemical: Bisphenol A

Low doses tested: 10, 100 or 1000 μg/kg bw/d

Route of administration: injected subcutaneously into pups

Exposure duration: post-natal day 1 – post-natal day 5 (comparable to human prenatal development from approximately day 1 of week 15 to day 1 of week 22)

Age of measurement: 18 months of age (late adulthood)

Reference [PubMed Link]
Newbold RR, Jefferson WN, Padilla-Banks E. 2007. Long-term adverse effects of neonatal exposure to bisphenol A on the murine female reproductive tract. Reprod Toxicol 24(2):253-258.
Study Results Study Details References

Results for Bisphenol A

Increased incidence of ovarian cysts at 100 μg/kg; also evidence (non-significant) of progressive proliferative lesions in all treated groups.

Subjects: CD-1 mice

Chemical: Bisphenol A

Low doses tested: 10, 100 or 1000 μg/kg bw/d

Route of administration: injected subcutaneously into pups

Exposure duration: post-natal day 1 – post-natal day 5 (comparable to human prenatal development from approximately day 1 of week 15 to day 1 of week 22)

Age of measurement: 18 months of age (late adulthood)

Reference [PubMed Link]
Newbold RR, Jefferson WN, Padilla-Banks E. 2007. Long-term adverse effects of neonatal exposure to bisphenol A on the murine female reproductive tract. Reprod Toxicol 24(2):253-258.