The weeks shown in color represent the start and end points of chemical exposure for each study.

Study Results Study Details References

Results for Bisphenol A

Early vaginal opening in females treated at 0.1 and 1.0 mg/kg doses.

Subjects: ICR mice

Chemical: Bisphenol A

Low doses tested: 0.1 or 1.0 mg/kg

Other doses tested: 10.0 and 100.0 mg/kg

Route of administration: dissolved in sesame oil and delivered subcutaneously

Exposure duration: post-natal day 8 – single dose (comparable to human prenatal development from approximately day 1 of week 25 to day 1 of week 26)

Age of measurement: post-natal day 10 to 70

Reference [PubMed Link]
Nah WH, Park MJ, Gye MC. 2011. Effects of early prepubertal exposure to bisphenol A on the onset of puberty, ovarian weights, and estrous cycle in female mice. Clin Exp Reprod Med 38(2):75-81.
Study Results Study Details References

Results for Bisphenol A

Decreased ovary weight on post-natal day 25 at 0.1 and 1.0 mg/kg doses and decreased ovary weight on post-natal day 30 in the 1.0 mg/kg group.

Subjects: ICR mice

Chemical: Bisphenol A

Low doses tested: 0.1 or 1.0 mg/kg

Other doses tested: 10.0 and 100.0 mg/kg

Route of administration: dissolved in sesame oil and delivered subcutaneously

Exposure duration: post-natal day 8 – single dose (comparable to human prenatal development from approximately day 1 of week 25 to day 1 of week 26)

Age of measurement: post-natal day 10 to 70

Reference [PubMed Link]
Nah WH, Park MJ, Gye MC. 2011. Effects of early prepubertal exposure to bisphenol A on the onset of puberty, ovarian weights, and estrous cycle in female mice. Clin Exp Reprod Med 38(2):75-81.