The weeks shown in color represent the start and end points of chemical exposure for each study.

Study Results Study Details References

Results for Chlorpyrifos

Delayed vaginal opening at 5 mg/kg

Subjects: Sprague-Dawley rats

Chemical: Chlorpyrifos

Low doses tested: 0.3, 1.0, or 5.0 mg/kg bw/d

Route of administration: dissolved in corn oil and delivered through gavage

Exposure duration: gestational day 6 – post-natal day 10 (comparable to human prenatal development from approximately day 1 of week 2 to day 1 of week 31)

Age of measurement: birth through adulthood

Reference [PubMed Link]
Maurissen JPJ, Hoberman AM, Garman RH, Hanley TR. 2000. Lack of selective developmental neurotoxicity in rat pups from dams treated by gavage with chlorpyrifos. Toxicol Sci 57(2):250-263.