The weeks shown in color represent the start and end points of chemical exposure for each study.

Study Results Study Details References

Results for Chlorpyrifos

Decreased ChE in serum

Subjects: Sprague Dawley rats

Chemical: Chlorpyrifos

Low doses tested: 1.0, 2.5, and 5.0 mg/kg bw/d

Route of administration: dissolved in corn oil and administered by gavage

Exposure duration: post-natal day 10 – post-natal day 16 (comparable to human prenatal development from approximately day 1 of week 30 to day 1 of week 37)

Age of measurement: post-natal day 16

Reference [PubMed Link]
Do RP, Stahlhut RW, Ponzi D, Vom Saal FS, Taylor JA. 2012. Non-monotonic dose effects of in utero exposure to di(2-ethylhexyl) phthalate (DEHP) on testicular and serum testosterone and anogenital distance in male mouse fetuses. Reprod Toxicol 34(4):614-621.
Study Results Study Details References

Results for Chlorpyrifos

Decreased ChE in serum

Subjects: Sprague Dawley rats

Chemical: Chlorpyrifos

Low doses tested: 1.0, 2.5, and 5.0 mg/kg bw/d

Route of administration: dissolved in corn oil and administered by gavage

Exposure duration: post-natal day 10 – post-natal day 16 (comparable to human prenatal development from approximately day 1 of week 30 to day 1 of week 37)

Age of measurement: post-natal day 16

Reference [PubMed Link]
Carr RL, Borazjani A, Ross MK. 2011. Effect of developmental chlorpyrifos exposure, on endocannabinoid metabolizing enzymes, in the brain of juvenile rats. Toxicol Sci 122(1):112-120.