The weeks shown in color represent the start and end points of chemical exposure for each study.
|Study Results||Study Details||References|
Results for ChlorpyrifosDecreased mitogenic response of T-cells on post-natal day 60 across two doses of concanavalin A
Subjects: Sprague-Dawley rats
Low doses tested: 5.0 mg/kg bw/d
Route of administration: dissolved in DMSO and injected subcutaneously
Exposure duration: post-natal day 11 – post-natal day 14 (comparable to human prenatal development from approximately day 1 of week 31 to day 1 of week 35)
Age of measurement: post-natal day 60
|Reference [PubMed Link]
Navarro HA, Basta PV, Seidler FJ, Slotkin TA. 2001. Neonatal chlorpyrifos administration elicits deficits in immune function in adulthood: a neural effect? Developmental Brain Research 130(2):249-252.