The weeks shown in color represent the start and end points of chemical exposure for each study.

Study Results Study Details References

Results for Chlorpyrifos

Decreased mitogenic response of T-cells on post-natal day 60 across two doses of concanavalin A

Subjects: Sprague-Dawley rats

Chemical: Chlorpyrifos

Low doses tested: 5.0 mg/kg bw/d

Route of administration: dissolved in DMSO and injected subcutaneously

Exposure duration: post-natal day 11 – post-natal day 14 (comparable to human prenatal development from approximately day 1 of week 31 to day 1 of week 35)

Age of measurement: post-natal day 60

Reference [PubMed Link]
Navarro HA, Basta PV, Seidler FJ, Slotkin TA. 2001. Neonatal chlorpyrifos administration elicits deficits in immune function in adulthood: a neural effect? Developmental Brain Research 130(2):249-252.