The weeks shown in color represent the start and end points of chemical exposure for each study.
| Study Results | Study Details | References |
Results for ChlorpyrifosDecreased body weight at 5 mg/kg |
Subjects: Sprague-Dawley rats Chemical: Chlorpyrifos Low doses tested: 0.3, 1.0, or 5.0 mg/kg bw/d Route of administration: dissolved in corn oil and delivered through gavage Exposure duration: gestational day 6 – post-natal day 10 (comparable to human prenatal development from approximately day 1 of week 2 to day 1 of week 31) Age of measurement: birth through adulthood |
Reference [PubMed Link] Maurissen JPJ, Hoberman AM, Garman RH, Hanley TR. 2000. Lack of selective developmental neurotoxicity in rat pups from dams treated by gavage with chlorpyrifos. Toxicol Sci 57(2):250-263. |
| Study Results | Study Details | References |
Results for ChlorpyrifosDecreased survival rate between birth and 4 days of age at 5 mg/kg; delayed pinna detachment at 5 mg/kg |
Subjects: Sprague-Dawley rats Chemical: Chlorpyrifos Low doses tested: 0.3, 1.0, or 5.0 mg/kg bw/d Route of administration: dissolved in corn oil and delivered through gavage Exposure duration: gestational day 6 – post-natal day 10 (comparable to human prenatal development from approximately day 1 of week 2 to day 1 of week 31) Age of measurement: birth through adulthood |
Reference [PubMed Link] Maurissen JPJ, Hoberman AM, Garman RH, Hanley TR. 2000. Lack of selective developmental neurotoxicity in rat pups from dams treated by gavage with chlorpyrifos. Toxicol Sci 57(2):250-263. |
| Study Results | Study Details | References |
Results for ChlorpyrifosIncreased post-weaning body weight among males |
Subjects: Long Evans rats Chemical: Chlorpyrifos Low doses tested: 2.5 mg/kg bw/d Route of administration: dissolved in corn oil and delivered through gavage Exposure duration: gestational day 7 – gestational day 21 (comparable to human prenatal development from approximately day 1 of week 2 to day 1 of week 16) Age of measurement: birth through adulthood |
Reference [PubMed Link] Lassiter TL, Brimijoin S. 2008. Rats gain excess weight after developmental exposure to the organophosphorothionate pesticide, chlorpyrifos. Neurotoxicology & Teratology 30(2):125-130. |