Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

imidacloprid

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CAS # 138261-41-3

Categories*
Household product ingredient
Pesticide ingredient

Evidence Supporting This Chemical as an Endocrine Disruptor

Bal R, Naziroglu M, Turk G, Yilmaz O, Kuloglu T, Etem E, Baydas G. 2012 Aug. Insecticide imidacloprid induces morphological and DNA damage through oxidative toxicity on the reproductive organs of developing male rats. Cell Biochem Funct 30(6):492-9.

Caron-Beaudoin, E, Viau, R, Hudon-Thibeault, AA, Vaillancourt, C, and Sanderson, JT. 2017. The use of a unique co-culture model of fetoplacental steroidogenesis as a screening tool for endocrine disruptors: The effects of neonicotinoids on aromatase activity and hormone production. Toxicology and applied pharmacology 332:15-24.

Kapoor U, Srivastava MK, Srivastava LP. 2011. Toxicological impact of technical imidacloprid on ovarian morphology, hormones and antioxidant enzymes in female rats. Food Chem Toxicol 49(12):3086-3089.

Kim J, Park Y, Yoon KS, Clark JM, Park Y. 2013. Imidacloprid, a neonicotinoid insecticide, induces insulin resistance. J Toxicol Sci 38(5):655-60.

Kugathas S, Audouze K, Ermler S, Orton F, Rosivatz E, Scholze M, Kortenkamp A. 2015 (in press). Effects of common pesticides on prostaglandin D2 (PGD2) inhibition in SC5 mouse Sertoli cells, evidence of binding at the COX2 active site, and implications for endocrine disruption. Environ Health Perspect.

Najafi G, Razi M, Hoshyar A, Shahmohamadloo S, Feyzi S. 2010. The Effect of Chronic Exposure with Imidacloprid Insecticide on Fertility in Mature Male Rats. International Journal of Fertility and Sterility 4(1):9-16.

Park Y, Kim Y, Kim J, Yoon KS, Clark J, Lee J, Park Y. 2013. Imidacloprid, a neonicotinoid insecticide, potentiates adipogenesis in 3T3-L1 adipocytes. J Agric Food Chem 61(1):255-259.

*Category References

Compendium of Pesticide Common Names (CPCN).

National Pesticide Information Retrieval System.

US Dept of Health & Human Services. Household Products Database.

US National Library of Medicine. Hazardous Substances Data Bank.

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