Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
2,3,7,8-tetrabromodibenzo-p-dioxin
CAS # 50585-41-6
Alternative Name
2,3,7,8-TBDD
Category*
Byproduct/Intermediate/Reactant
Evidence Supporting This Chemical as an Endocrine Disruptor
Hornung MW, Zabel EW, Peterson RE. 1996. Toxic equivalency factors of polybrominated dibenzo-p-dioxin, dibenzofuran, biphenyl, and polyhalogenated diphenyl ether congeners based on rainbow trout early life stage mortality. Toxicol Appl Pharmacol 140(2):227-234.
Ivens IA, Loser E, Rinke M, Schmidt U, Mohr U. 1993. Subchronic toxicity of 2,3,7,8-tetrabromodibenzo-p-dioxin in rats. Toxicology 83(1-3):181-201.
Kedderis LB, Diliberto JJ, Jackson JA, Linko P, Goldstein JA, Birnbaum LS. 1992. Effects of dose and route of exposure on dioxin disposition. Chemosphere 25(1-2):7-10.
*Category References
Hornung MW, Zabel EW, Peterson RE. 1996. Toxic equivalency factors of polybrominated dibenzo-p-dioxin, dibenzofuran, biphenyl, and polyhalogenated diphenyl ether congeners based on rainbow trout early life stage mortality. Toxicol Appl Pharmacol 140(2):227-234.
WHO. 1994. Brominated diphenyl ethers. Environmental Health Criteria 162.