Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
2-hydroxychrysene
CAS # 65945-06-4
Alternative Names
2-OH-CR
2-chrysenol
Categories*
Medical/Veterinary/Research
Metabolite/Degradate
Evidence Supporting This Chemical as an Endocrine Disruptor
Fertuck KC, Kumar S, Sikka HC, Matthews JB, Zacharewski TR. 2001. Interaction of PAH-related compounds with the alpha and beta isoforms of the estrogen receptor. Toxicol Lett 121(3):167-177.
van Lipzig MM, Vermeulen NP, Gusinu R, Legler J, Frank H, Seidel A, Meerman JH. 2005. Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity. Environ Toxicol Pharmacol 19(1):41-55.
*Category References
Fertuck KC, Kumar S, Sikka HC, Matthews JB, Zacharewski TR. 2001. Interaction of PAH-related compounds with the alpha and beta isoforms of the estrogen receptor. Toxicol Lett 121(3):167-177.
van Lipzig MM, Vermeulen NP, Gusinu R, Legler J, Frank H, Seidel A and Meerman JH. 2005. Formation of estrogenic metabolites of benzo[a]pyrene and chrysene by cytochrome P450 activity and their combined and supra-maximal estrogenic activity. Environ Toxicol Pharmacol 19(1): 41-55.