Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
3'-hydroxy-2,2',3,4,4',5,5'-heptachlorobiphenyl
CAS # 158076-69-8
Alternative Names
3'-OH-PCB-180
2,2',3',4,4',5,5'-heptachloro-3-biphenylol
HO-PCB3
Category*
Metabolite/Degradate
Evidence Supporting This Chemical as an Endocrine Disruptor
Kester MH, Bulduk S, Tibboel D, Meinl W, Glatt H, Falany CN, Coughtrie MW, Bergman A, Safe SH, Kuiper GG, Schuur AG, Brouwer A, Visser TJ. 2000 . Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs. Endocrinology 141(5):1897–1900.
*Category References
Kester M H, Bulduk S, Tibboel D, Meinl W, Glatt H, Falany CN, Coughtrie MW, Bergman A, Safe SH, Kuiper GG, Schuur AG, Brouwer A and Visser TJ. 2000. Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs. Endocrinology 141(5):1897–1900.