Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
3-hydroxybenzo[a]pyrene
CAS # 13345-21-6
Alternative Name
3-OH-B[a]P
Category*
Metabolite/Degradate
Evidence Supporting This Chemical as an Endocrine Disruptor
Fertuck KC, Matthews JB, Zacharewski TR. 2001. Hydroxylated benzo[a]pyrene metabolites are responsible for in vitro estrogen receptor-mediated gene expression induced by benzo[a]pyrene, but do not elicit uterotrophic effects in vivo. Toxicol Sci 59(2):231-240.
*Category References
Fertuck KC, Matthews JB and Zacharewski TR. 2001. Hydroxylated benzo[a]pyrene metabolites are responsible for in vitro estrogen receptor-mediated gene expression induced by benzo[a]pyrene, but do not elicit uterotrophic effects in vivo. Toxicol Sci 59(2): 231-240.