Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

4'-hydroxy-3,3',4,5'-tetrachlorobiphenyl

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CAS # 111810-41-4

Alternative Name

4'-OH-PCB-79

Category*
Metabolite/Degradate

Evidence Supporting This Chemical as an Endocrine Disruptor

Kester MH, Bulduk S, Tibboel D, Meinl W, Glatt H, Falany CN, Coughtrie MW, Bergman A, Safe SH, Kuiper GG, Schuur AG, Brouwer A, Visser TJ. 2000 . Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs. Endocrinology 141(5):1897–1900.

*Category References

Kester M H, Bulduk S, Tibboel D, Meinl W, Glatt H, Falany CN, Coughtrie MW, Bergman A, Safe SH, Kuiper GG, Schuur AG, Brouwer A and Visser TJ. 2000. Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs. Endocrinology 141(5):1897–1900.

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