Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

4-hydroxy-1,3,6,7-tetrachlorodibenzofuran

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CAS #

Category*
Metabolite/Degradate

Evidence Supporting This Chemical as an Endocrine Disruptor

Kester MH, Bulduk S, van Toor H, Tibboel D, Meinl W, Glatt H, Falany CN, Coughtrie MW, Schuur AG, Brouwer A, Visser TJ. 2002. Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters. J Clin Endocrinol Metab 87(3):1142-1150.

*Category References

Kester MH, Bulduk S, van Toor H, Tibboel D, Meinl W, Glatt H, Falany CN, Coughtrie MW, Schuur AG, Brouwer A and Visser TJ. 2002. Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters. Journal of Clinical Endocrinology and Metabolism 87(3): 1142-1150.

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