Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
2,4,4'-trichlorobiphenyl
CAS # 7012-37-5
Alternative Name
PCB-28
Category*
Industrial additive
Evidence Supporting This Chemical as an Endocrine Disruptor
Chu I, Villeneuve DC, Yagminas A, Lecavalier P, Poon R, Hakansson H, Ahlborg UG, Valli VE, Kennedy SW, Bergman A, Seegal RF, Feeley M. 1996. Toxicity of 2,4,4'-trichlorobiphenyl in rats following 90-day dietary exposure. J Toxicol Environ Health 49(3):301-318.
Ness DK, Schantz SL, Moshtaghian J, Hansen LG. 1993. Effects of perinatal exposure to specific to PCB congeners on thyroid hormone concentrations and thyroid histology in the rat. Toxicol Lett 68(3):311-323.
Schantz SL, Seo B-W, Moshtaghian J, Amin S. 1997. Developmental exposure to polychlorinated biphenyls or dioxin: do changes in thyroid function mediate effects on spatial learning? Am Zool 37(4):399-408.
*Category References
CDPH. 1988. Polychlorinated Biphenyls (PCBs). Fact Sheet.
UNEP. 1999. Guidlines for the Identification of PCBs and Materials Containing PCBs.
US EPA. 2012. Aroclor and other PCB mixtures.