Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

p-cumylphenol

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CAS # 599-64-4

Alternative Names

4-(1-methyl-1-phenethyl)-Phenol

4-alpha-cumylphenol

Categories*
Byproduct/Intermediate/Reactant
Plastic/Rubber

Evidence Supporting This Chemical as an Endocrine Disruptor

Fang H, Tong WD, Branham WS, Moland CL, Dial SL, Hong HX, Xie Q, Perkins R, Owens W, Sheehan DM. 2003. Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. Chem Res Toxicol 16(10):1338-1358.

Matsushima A, Teramoto T, Okada H, Liu X, Tokunaga T, Kakuta Y, Shimohigashi Y. 2008. ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner. Biochem Biophys Res Commun 373(3):408-413.

Terasaki M, Shiraishi F, Nishikawa T, Edmonds JS, Morita M, Makino M. 2005. Estrogenic activity of impurities in industrial grade bisphenol A. Environ Sci Technol 39(10):3703-3707.

*Category References

Terasaki M, Shiraishi F, Nishikawa T, Edmonds JS, Morita M and Makino M. 2005. Estrogenic activity of impurities in industrial grade bisphenol A. Environ Sci Technol 39(10):3703-3707.

US National Library of Medicine. Hazardous Substances Data Bank.

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