Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
2,4,5-trichlorophenoxyacetic acid
CAS # 93-76-5
Alternative Name
2,4,5-T
Category*
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Goldner WS, Sandler DP, Yu F, Shostrom V, Hoppin JA, Kamel F, LeVan TD. Hypothyroidism and pesticide use among male private pesticide applicators in the agricultural health study. Journal of occupational and environmental medicine/American College of Occupational and Environmental Medicine. 2013 Oct;55(10):1171.
Kim CS, Keizer RF, Ambrose WW, Breese GR. 1987. Effects of 2,4,5-trichlorophenoxyacetic acid and quinolinic acid on 5- hydroxy-3-indoleacetic acid transport by the rabbit choroid plexus: pharmacology and electron microscopic cytochemistry. Toxicol Appl Pharmacol 90(3):436-444.
Van den Berg KJ, van Raaij JAGM, Bragt PC, Notten WRF. 1991. Interactions of halogenated industrial chemicals with transthyretin and effects on thyroid hormone levels in vivo. Arch Toxicol 65(1):15-19.
*Category References
Compendium of Pesticide Common Names (CPCN).
US National Library of Medicine. Haz-Map.
US National Library of Medicine. Hazardous Substances Data Bank.