CAS #
Alternative Names
mix of 9,12-oxy-10,13-dihydroxyoctadecanoic acid and 10,13-oxy-9,12- dihydroxyoctadecanoic acid
THF-diols
Categories*
Biogenic compound
Byproduct/Intermediate/Reactant
Medical/Veterinary/Research
Evidence Supporting This Chemical as an Endocrine Disruptor
Markaverich BM, Alejandro M, Thompson T, Mani S, Reyna A, Portillo W, Sharp J, Turk J, Crowley JR. 2007. Tetrahydrofurandiols (THF-diols), leukotoxindiols (LTX-diols), and endocrine disruption in rats. Environ Health Perspect 115(5):702-708.
Markaverich BM, Crowley J, Rodriquez M, Shoulars K, Thompson T. 2007. Tetrahydrofurandiol stimulation of phospholipase A(2), lipoxygenase, and cyclooxygenase gene expression and MCF-7 human breast cancer cell proliferation. Environ Health Perspect 115(12):1727-1731.
*Category References
Markaverich BM, Alejandro M, Thompson T, Mani S, Reyna A, Portillo W, Sharp J, Turk J and Crowley JR. 2007. Tetrahydrofurandiols (THF-diols), leukotoxindiols (LTX-diols), and endocrine disruption in rats. Environmental Health Perspectives 115(5): 702-708.