Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
(E)-crotonaldehyde
CAS # 123-73-9
Alternative Names
E-2-butenal
crotonaldehyde
Categories*
Byproduct/Intermediate/Reactant
Food additives and contact material
Household product ingredient
Pesticide ingredient
Plastic/Rubber
Solvent
Unconventional Oil and Gas
Evidence Supporting This Chemical as an Endocrine Disruptor
Grundfest CC, Chang J, Newcombe D. 1982. Acrolein: a potent modulator of lung macrophage arachidonic acid metabolism. Biochim Biophys Acta 713(1):149-159.
Jha AM, Kumar M. 2006. In vivo evaluation of induction of abnormal sperm morphology in mice by an unsaturated aldehyde crotonaldehyde. Mutat Res 603(2):159-163.
*Category References
US National Library of Medicine. Hazardous Substances Data Bank.
Waxman HA, Markey EJ, and DeGette D. 2011. Chemicals used in hydraulic fracturing. United States House of Representatives Committee on Energy and Commerce Minority Staff.