Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

hexacanoic acid

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CAS # 57-10-3

Alternative Names

palmitic acid

palmitate

Categories*
Byproduct/Intermediate/Reactant
Food additives and contact material
Household product ingredient
Metal/Metallurgy
Personal care product/Cosmetic ingredient
Unconventional Oil and Gas

Evidence Supporting This Chemical as an Endocrine Disruptor

Azevedo-Martins AK, Monteiro AP, Lima CL, Lenzen S, Curi R. 2006. Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. Toxicol In Vitro 20(7):1106-1113.

Beeharry N, Lowe JE, Hernandez AR, Chambers JA, Fucassi F, Cragg PJ, Green MH, Green IC. 2003. Linoleic acid and antioxidants protect against DNA damage and apoptosis induced by palmitic acid. Mutat Res 530(1-2):27-33.

Xiao J, Gregersen S, Pedersen SB, Hermansen K. 2002. Differential impact of acute and chronic lipotoxicity on gene expression in INS-1 cells. Metabolism 51(2):155-162.

*Category References

The Endocrine Disruption Exchange. 2011. Multistate Report Spreadsheet.

US National Library of Medicine. Hazardous Substances Data Bank.

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