Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
hexaldehyde
CAS # 66-25-1
Categories*
Byproduct/Intermediate/Reactant
Food additives and contact material
Pesticide ingredient
Plastic/Rubber
Unconventional Oil and Gas
Evidence Supporting This Chemical as an Endocrine Disruptor
Suarez-Pinzon WL, Strynadka K, Rabinovitch A. 1996. Destruction of rat pancreatic islet beta-cells by cytokines involves the production of cytotoxic aldehydes. Endocrinology, 137(12):5290-5296.
Villard PH, Barlesi F, Armand M, Pascussi JM, Fouchier F, Champion S, Dufour C, Giniès C, Khalil A, Amiot MJ, and Barra Y. 2011. CYP1A1 induction in the colon by serum: involvement of the PPARα pathway and evidence for a new specific human PPREα site. PloS One 6(1):e14629.
*Category References
Colborn T, Schultz K, Herrick L, Kwiatkowski C. 2014. An Exploratory Study of Air Quality near Natural Gas Operations. Hum Ecol Risk Assess 20(1):86-105.
US National Library of Medicine. Hazardous Substances Data Bank.