Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
2,8-dibromo-3,7-dichlorodibenzo-p-dioxin
CAS # 109333-32-6
Alternative Name
2,8-dichloro-3,7-dibromodibenzodioxin
Categories*
Byproduct/Intermediate/Reactant
Medical/Veterinary/Research
Evidence Supporting This Chemical as an Endocrine Disruptor
Hornung MW, Zabel EW, Peterson RE. 1996. Toxic equivalency factors of polybrominated dibenzo-p-dioxin, dibenzofuran, biphenyl, and polyhalogenated diphenyl ether congeners based on rainbow trout early life stage mortality. Toxicol Appl Pharmacol 140(2):227-234.
*Category References
Mason G, Zacharewski T, Denomme MA, Safe L, Safe S. 1987. Polybrominated dibenzo-p-dioxins and related compounds: Quantitative in vivo and in vitro structure-activity relationships. Toxicology 44(3):245-255.
Schulz-Schalge T, Koch E, Schwind KH, Hutzinger O, Neubert D. 1991. Inductive potency of TCDD, TBDD and three 2,3,7,8-mixed-halogenated dioxins in liver microsomes of male rats. Enzyme kinetic considerations. Chemosphere 23(11-12):1925-1931.