Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
3,3',4,4',5,5'-hexachlorobiphenyl
CAS # 32774-16-6
Alternative Name
PCB-169
Category*
Industrial additive
Evidence Supporting This Chemical as an Endocrine Disruptor
Krishnan V, Safe S. 1993. Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), and dibenzofurans (PCDFs) as antiestrogens in MCF-7 human breast cancer cells: quantitative structure-activity relationships. Toxicol Appl Pharmacol 120(1):55-61.
Patnode KA, Curtis LR. 1994. 2,2',4,4',5,5'- and 3,3',4,4',5,5'-hexachlorobiphenyl alteration of uterine progesterone and estrogen receptors coincides with embryotoxicity in mink (Mustela vison). Toxicol Appl Pharmacol 127(1):9-18.
*Category References
CDPH. 1988. Polychlorinated Biphenyls (PCBs). Fact Sheet.
UNEP. 1999. Guidlines for the Identification of PCBs and Materials Containing PCBs.
US EPA. 2012. Aroclor and other PCB mixtures.