Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
1,2,4,8-tetrachlorodibenzofuran
CAS # 64126-87-0
Alternative Name
1,2,4,8-TCDF
Category*
Byproduct/Intermediate/Reactant
Evidence Supporting This Chemical as an Endocrine Disruptor
Bandiera S, Sawyer T, Romkes M, Zmudzka B, Safe L, Mason G, Keys B, Safe S. 1984. Polychlorinated dibenzofurans (PCDFs): effects of structure on binding to the 2,3,7,8-TCDD cytosolic receptor protein, AHH induction and toxicity. Toxicology 32(2):131-144.
*Category References
ATSDR. 1994. Toxicological profile for Chlorodibenzofurans.
Bandiera S, Sawyer T, Romkes M, Zmudzka B, Safe L, Mason G, Keys B, Safe S. 1984. Polychlorinated dibenzofurans (PCDFs): effects of structure on binding to the 2,3,7,8-TCDD cytosolic receptor protein, AHH induction and toxicity. Toxicology 32(2):131-144.
Mason G, Sawyer T, Keys B, Bandiera S, Romkes M, Piskorska-Pliszczynska J, Zmudzka B, Safe S. 1985. Polychlorinated dibenzofurans (PCDFs): correlation between in vivo and in vitro structure-activity relationships. Toxicology 37(1-2):1-12.