Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
4-benzylphenol
CAS # 101-53-1
Alternative Names
p-benzylphenol
4-hydroxydiphenylmethane
4-(phenylmethyl)phenol
phenyl-4-hydroxyphenylmethane
1-(phenyl)-1-(p-hydroxyphenyl)methane
Categories*
Medical/Veterinary/Research
Plastic/Rubber
Evidence Supporting This Chemical as an Endocrine Disruptor
Akahori Y, Nakai M, Yamasaki K, Takatsuki M, Shimohigashi Y, Ohtaki M. 2008. Relationship between the results of in vitro receptor binding assay to human estrogen receptor alpha and in vivo uterotrophic assay: Comparative study with 65 selected chemicals. Toxicol in Vitro 22(1):225-231.
Hashimoto Y, Moriguchi Y, Oshima H, Kawaguchi M, Miyazaki K, Nakamura M. 2001. Measurement of estrogenic activity of chemicals for the development of new dental polymers. Toxicol in Vitro 15(4-5):421-425.
Kitamura S, Sanoh S, Kohta R, Suzuki T, Sugihara K, Fujimoto N, Ohta S. 2003. Metabolic activation of proestrogenic diphenyl and related compounds by rat liver microsomes. Journal of Health Science 49(4):298-310.
Yamasaki K, Takeyoshi M, Sawaki M, Imatanaka N, Shinoda K, Takatsuki M. 2003. Immature rat uterotrophic assay of 18 chemicals and Hershberger assay of 30 chemicals. Toxicology 183(1-3):93-115.
Yamasaki K, Takeyoshi M, Yakabe Y, Sawaki M, Takatsuki M. 2003. Comparison of the reporter gene assay for ERalpha antagonists with the immature rat uterotrophic assay of 10 chemicals. Toxicol Lett 142(1-2):119-131.
*Category References
Hashimoto Y, Moriguchi Y, Oshima H, Kawaguchi M, Miyazaki K, Nakamura M. 2001. Measurement of estrogenic activity of chemicals for the development of new dental polymers. Toxicol in Vitro 15(4-5):421-425.