Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
4-chloro-3,5-dimethylphenol
CAS # 88-04-0
Alternative Names
4-chloro-3,5-xylenol
chloroxylenol
p-chloro-m-xylenol (PCMX)
Categories*
Antimicrobial
Household product ingredient
Personal care product/Cosmetic ingredient
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Miller D, Wheals BB, Beresford N, Sumpter JP. 2001. Estrogenic activity of phenolic additives determined by an in vitro yeast bioassay. Environ Health Perspect 109(2):133-138.
Nakama A, Funasaka K, Shimizu M. 2007. Evaluation of estrogenic activity of organic biocides using ER-binding and YES assay. Food Chem Toxicol 45(9):1558-1564.
Nishihara T, Nishikawa J, Kanayama T, Dakeyama F, Saito K, Imagawa M, Takatori S, Kitagawa Y, Hori S, Utsumi H. 2000. Estrogenic activities of 517 chemicals by yeast two-hybrid assay. Journal of Health Science 46(4):282-298.
*Category References
US Dept of Health & Human Services. Household Products Database.
US EPA. InertFinder.
US National Library of Medicine. Haz-Map.
US National Library of Medicine. Hazardous Substances Data Bank.