Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

4'-hydroxy-2,3',4,5,5'-pentachlorobiphenyl

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CAS # 149589-56-0

Alternative Names

4'-OH-PCB-120

4-hydroxy-2´,3,4´,5,5´-pentachlorobiphenyl

Category*
Metabolite/Degradate

Evidence Supporting This Chemical as an Endocrine Disruptor

Kramer VJ, Giesy JP. 1999. Specific binding of hydroxylated polychlorinated biphenyl metabolites and other substances to bovine calf uterine estrogen receptor: structure-binding relationships. Sci Total Environ 233(1-3):141-161.

Schuur AG, Brouwer A, Bergman A, Coughtrie MWH, Visser TJ. 1998. Inhibition of thyroid hormone sulfation by hydroxylated metabolites of polychlorinated biphenyls. Chem Biol Interact 109(1-3):293-297.

*Category References

ATSDR. 2000. Toxicological Profile for Polychlorinated Biphenyls (PCBs).

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