Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

4-nitrophenol

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CAS # 100-02-7

Alternative Name

p-nitrophenol

Categories*
Antimicrobial
Byproduct/Intermediate/Reactant
Industrial additive
Pesticide ingredient
Plastic/Rubber

Evidence Supporting This Chemical as an Endocrine Disruptor

Li C, Taneda S, Suzuki AK, Furuta C, Watanabe G, Taya K. 2006. Estrogenic and anti-androgenic activities of 4-nitrophenol in diesel exhaust particles. Toxicol Appl Pharmacol 217(1):1-6.

Li X, Li C, Suzuki AK, Taneda S, Watanabe G, Taya K. 2009. 4-Nitrophenol isolated from diesel exhaust particles disrupts regulation of reproductive hormones in immature male rats. Endocrine 36(1):98-102.

Mi Y, Zhang C, Li CM, Taneda S, Watanabe G, Suzuki AK, Taya K. 2010. Protective effect of quercetin on the reproductive toxicity of 4-nitrophenol in diesel exhaust particles on male embryonic chickens. J Reprod Dev 56(2):195-199.

*Category References

US EPA. InertFinder.

US National Library of Medicine. Haz-Map.

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