Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
6-hydroxychrysene
CAS # 37515-51-8
Categories*
Byproduct/Intermediate/Reactant
Metabolite/Degradate
Evidence Supporting This Chemical as an Endocrine Disruptor
Jin L, Tran DQ, Ide CF, McLachlan JA, Arnold SF. 1997. Several synthetic chemicals inhibit progesterone receptor-mediated transactivation in yeast. Biochemical & Biophysical Research Communications 233(1):139-146.
Tran DQ, Ide CF, McLachlan JA, Arnold SF. 1996. The anti-estrogenic activity of selected polynuclear aromatic hydrocarbons in yeast expressing human estrogen receptor. Biochem Biophys Res Commun 229(1):102-108.
*Category References
Buratti M, Campo L, Fustinoni S, Cirla PE, Martinotti I, Cavallo D, Foa V. 2007. Urinary hydroxylated metabolites of polycyclic aromatic hydrocarbons as biomarkers of exposure in asphalt workers. Biomarkers 12(3):221-239.