Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
alpha-tocopherol
CAS # 59-02-9 / 1406-18-4
Alternative Name
vitamin E
Categories*
Biogenic compound
Food additives and contact material
Medical/Veterinary/Research
Personal care product/Cosmetic ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Rosenberg RS, Grass L, Jenkins DJ, Kendall CWC, Diamandis EP. 1998. Modulation of androgen and progesterone receptors by phytochemicals in breast cancer cell lines. Biochemical & Biophysical Research Communications 248(3):935-939.
*Category References
Australia New Zealand Food Standards Code. Standard 1.2.4 - Labelling of ingredients.
PUBCHEM. Tocopherols.
UK Food Standards Agency. Current EU approved additives and their E Numbers.
US FDA. 2012. Food Additive Status List.
US National Library of Medicine. Hazardous Substances Data Bank.
Weiser H, Riss G, Kormann AW. 1996. Biodiscrimination of the eight alpha-tocopherol stereoisomers results in preferential accumulation of the four 2R forms in tissues and plasma of rats. J Nutr 126(10):2539-2549.