Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
amitrole
CAS # 61-82-5
Alternative Names
aminotriazole
aminotriazol
amitrol
2-amino-1,3,4-triazole
3-amino-1,2,4-triazole
Categories*
Medical/Veterinary/Research
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Fregly MJ. 1968. Effect of aminotriazole on thyroid function in the rat. Toxicol Appl Pharmacol 13(3):271-286.
Hurley PM, Hill RN, Whiting RJ. 1998. Mode of carcinogenic action of pesticides inducing thyroid follicular cell tumors in rodents [review]. Environ Health Perspect 106(8):437-445.
Jukes TH, Shaffer CB. 1960. Antithyroid effects of aminotriazole. Science 132(3422):296-297.
Steinhoff D, Weber H, Mohr U, Boehme K. 1983. Evaluation of amitrole (aminotriazole) for potential carcinogenicity in orally dosed rats, mice, and golden hamsters. Toxicol Appl Pharmacol 69(2):161-169.
*Category References
Compendium of Pesticide Common Names (CPCN).
Heim WG, Appleman D, Pyfrom HT. 1955. Production of catalase changes in animals with 3-amino-1, 2, 4-triazole. Science 122(3172):693-694.
US National Library of Medicine. Haz-Map.