Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
arsenic
CAS # 7440-38-2
Categories*
Byproduct/Intermediate/Reactant
Industrial additive
Metal/Metallurgy
Pesticide ingredient
Unconventional Oil and Gas
Evidence Supporting This Chemical as an Endocrine Disruptor
Bodwell JE, Gosse JA, Nomikos AP, Hamilton JW. 2006. Arsenic disruption of steroid receptor gene activation: Complex dose-response effects are shared by several steroid receptors. Chem Res Toxicol 19(12):1619-1629.
Bodwell JE, Kingsley LA, Hamilton JW. 2004. Arsenic at very low concentrations alters glucocorticoid receptor (GR)-mediated gene activation but not GR-mediated gene repression: complex dose-response effects are closely correlated with levels of activated GR and require a functional GR DNA binding domain. Chem Res Toxicol 17(8):1064-1076.
Meeker JD, Rossano MG, Protas B, Diamond MP, Puscheck E, Daly D, Paneth N, Wirth JJ. 2009. Multiple metals predict prolactin and thyrotropin (TSH) levels in men. Environ Res 109(7):869-873.
*Category References
Alawattegama SK, Kondratyuk T, Krynock R, Bricker M, Rutter JK, Bain DJ, Stolz JF. 2015. Well water contamination in a rural community in southwestern Pennsylvania near unconventional shale gas extraction. J Environ Sci Health A Tox Hazard Subst Environ Eng 50(5):516-528.
Hood E. 2006. The Apple Bites Back: Claiming Old Orchards for Residential Development. Environ Health Perspect 114(8):A470-A476.
Maguire-Boyle SJ, Barron AR. 2014. Organic compounds in produced waters from shale gas wells. Environ Sci Process Impacts 16(10):2237-2248.
US Dept of Health & Human Services. Household Products Database.
US EPA. 2011. Chromated Copper Arsenate (CCA).
US National Library of Medicine. Haz-Map.
US National Library of Medicine. Hazardous Substances Data Bank. (arsenic compounds)
Zielinska B, Campbell D, Samburova V. 2014. Impact of emissions from natural gas production facilities on ambient air quality in the Barnett Shale area: a pilot study. J Air Waste Manag Assoc 64(12):1369-1383.