Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
benzo[a]pyrene
CAS # 50-32-8
Alternative Names
benz[a]pyrene
benzo(d,e,f)chrysene
Categories*
Byproduct/Intermediate/Reactant
Medical/Veterinary/Research
Unconventional Oil and Gas
Evidence Supporting This Chemical as an Endocrine Disruptor
Machala M, Vondracek J, Blaha L, Ciganek M, Neca JV. 2001. Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay. Mutat Res 497(1-2):49-62.
Thomas P. 1990. Teleost model for studying the effects of chemicals on female reproductive endocrine function. J Exp Zool Suppl 4:126-128.
Vinggaard AM, Hnida C, Larsen JC. 2000. Environmental polycyclic aromatic hydrocarbons affect androgen receptor activation in vitro. Toxicology 145(2-3):173-183.
*Category References
ATSDR. 1995. Toxicological Profile for Polycyclic Aromatic Hydrocarbons.
Colborn T, Schultz K, Herrick L, Kwiatkowski C. 2014. An Exploratory Study of Air Quality near Natural Gas Operations. Hum Ecol Risk Assess 20(1):86-105.
Paulik LB, Donald CE, Smith BW, Tidwell LG, Hobbie KA, Kincl L, Haynes EN, and Anderson KA, 2016. Emissions of Polycyclic Aromatic Hydrocarbons from Natural Gas Extraction into Air. Environ Sci Technol 50(14):7921-7929.
US National Library of Medicine. Haz-Map.
US National Library of Medicine. Hazardous Substances Data Bank.
Zielinska B, Campbell D, Samburova V. 2014. Impact of emissions from natural gas production facilities on ambient air quality in the Barnett Shale area: a pilot study. J Air Waste Manag Assoc 64(12):1369-1383.