Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
1-hydroxypyrene
CAS # 5315-79-7
Category*
Metabolite/Degradate
Evidence Supporting This Chemical as an Endocrine Disruptor
Jin L, Tran DQ, Ide CF, McLachlan JA, Arnold SF. 1997. Several synthetic chemicals inhibit progesterone receptor-mediated transactivation in yeast. Biochemical & Biophysical Research Communications 233(1):139-146.
*Category References
Jongeneelen FJ. 2001. Benchmark guideline for urinary 1-hydroxypyrene as biomarker of occupational exposure to polycyclic aromatic hydrocarbons. Ann Occup Hyg 45(1):3-13.