Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
carbaryl
CAS # 63-25-2
Alternative Names
carbaril
sevin
Categories*
Household product ingredient
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Casale GP, Vennerstrom JL, Bavari S, Wang T. 1993. Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected carbamate and organophosphate insecticides and congeners of carbaryl. Immunopharmacology & Immunotoxicology 15(2 & 3):199-215.
Dieringer CS, Thomas JA. 1974. Effects of carbaryl on the metabolism of androgens in the prostate and liver of the mouse. Environ Res 7(3):381-386.
Hassan A. 1971. Pharmacological effects of carbaryl. I. The effect of carbaryl on the synthesis and degradation of catecholamines in the rat. Biochem Pharmacol 20(9):2299-308.
Klotz DM, Arnold SF, McLachlan JA. 1997. Inhibition of 17 beta-estradiol and progesterone activity in human breast and endometrial cancer cells by carbamate insecticides. Life Sci 60(17):1467-1475.
Smalley HE, Curtis JM, Earl FL. 1968. Teratogenic action of carbaryl in beagle dogs. Toxicol Appl Pharmacol 13(3):392-403.
*Category References
Compendium of Pesticide Common Names (CPCN).
US Dept of Health & Human Services. Household Products Database.
US National Library of Medicine. Haz-Map.
US National Library of Medicine. Hazardous Substances Data Bank.