Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
carbendazim
CAS # 10605-21-7
Categories*
Metabolite/Degradate
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Goldman JM, Rehnberg GL, Cooper RL, Gray LE, Hein JF, McElroy WK. 1989. Effects of the benomyl metabolite, carbendazim, on the hypothalamic-pituitary reproductive axis in the male rat. Toxicology 57(2):173-182.
Lim J, Miller MG. 1997. Role of testis exposure levels in the insensitivity of prepubertal rats to carbendazim-induced testicular toxicity. Fundam Appl Toxicol 37(2):158-167.
*Category References
Compendium of Pesticide Common Names (CPCN).
Morinaga H, Yanase T, Nomura M, Okabe T, Goto K, Harada N, Nawata H. 2004. A benzimidazole fungicide, benomyl, and its metabolite, carbendazim, induce aromatase activity in a human ovarian granulose-like tumor cell line (KGN). Endocrinology 145(4):1860-1869.
US National Library of Medicine. Haz-Map.
US National Library of Medicine. Hazardous Substances Data Bank.