Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
cypermethrin
CAS # 52315-07-8
Alternative Name
cyano(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
Categories*
Household product ingredient
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Du G, Shen O, Sun H, Fei J, Lu C, Song L, Xia Y, Wang S, Wang X. 2010. Assessing hormone receptor activities of pyrethroid insecticides and their metabolites in reporter gene assays. Toxicol Sci 116(1):58-66.
Kojima H, Katsura E, Takeuchi S, Niiyama K, Kobayashi K. 2004. Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Environ Health Perspect 112(5):524-531.
Kugathas S, Audouze K, Ermler S, Orton F, Rosivatz E, Scholze M, Kortenkamp A. 2015 (in press). Effects of common pesticides on prostaglandin D2 (PGD2) inhibition in SC5 mouse Sertoli cells, evidence of binding at the COX2 active site, and implications for endocrine disruption. Environ Health Perspect.
Moore A, Waring CP. 2001. The effects of a synthetic pyrethroid pesticide on some aspects of reproduction in Atlantic salmon (Salmo salar L.). Aquatic Toxicology 52(1):1-12.
Varshneya C, Singh T, Sharma LD, Bahga HS, Garg SK. 1992. Immunotoxic responses of cypermethrin, a synthetic pyrethroid insecticide in rats. Indian Journal of Physiology & Pharmacology 36(2):123-126.
*Category References
Compendium of Pesticide Common Names (CPCN).
US Dept of Health & Human Services. Household Products Database.
US EPA, OPPTS. 2006 Jun 14 (revised 01/14/08). Reregistration Eligibility Decision for Cypermethrin. EPA OPP-2005-0293. (p. 17)
US National Library of Medicine. Haz-Map.