Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

dieldrin

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CAS # 60-57-1

Category*
Pesticide ingredient

Evidence Supporting This Chemical as an Endocrine Disruptor

Abalis IM, Eldefrawi ME, Eldefrawi AT. 1985. High-affinity stereospecific binding of cyclodiene insecticides and gamma-hexachlorocyclohexane to gamma-aminobutyric acid receptors of rat brain. Pesticide Biochemistry & Physiology 24(1):95-102.

Danzo BJ. 1997. Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins. Environ Health Perspect 105(3):294-301.

Grunfeld HT, Bonefeld-Jorgensen EC. 2004. Effect of in vitro estrogenic pesticides on human oestrogen receptor alpha and beta mRNA levels. Toxicol Lett 151(3):467-480.

Haake J, Kelley M, Keys B, Safe S. 1987. The effects of organochlorine pesticides as inducers of testosterone and benzo[a]pyrene hydroxylases. Gen Pharmacol 18(2):165-169.

Soto AM, Chung KL, Sonnenschein C. 1994. The pesticides endosulfan, toxaphene and dieldrin have estrogenic properties in human estrogen-sensitive cells. Environ Health Perspect 102(4):380-383.

Wassermann M, Wassermann D, Kedar E, Djavaherian M, Cucos S. 1972. Effects of dieldrin and gamma BHC on serum proteins and PBI. Bull Environ Contam Toxicol 8(3):177-185.

*Category References

CDC.

Compendium of Pesticide Common Names (CPCN).

US National Library of Medicine. Haz-Map.

US National Library of Medicine. Hazardous Substances Data Bank.

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