Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
dihexyl phthalate
CAS # 84-75-3
Alternative Names
DHP
di-n-hexylphthalate (DnHP)
Categories*
Byproduct/Intermediate/Reactant
Household product ingredient
Industrial additive
Plastic/Rubber
Evidence Supporting This Chemical as an Endocrine Disruptor
Lu KY, Tseng FW, Wu CJ, Liu PS. 2004. Suppression by phthalates of the calcium signaling of human nicotinic acetylcholine receptors in human neuroblastoma SH-SY5Y cells. Toxicology 200(2-3):113-121.
Saillenfait AM, Gallissot F, Sabate JP. 2009. Differential developmental toxicities of di-n-hexyl phthalate and dicyclohexyl phthalate administered orally to rats. J Appl Toxicol 29(6):510-521.
Saillenfait AM, Sabate JP, Gallissot F. 2009. Effects of in utero exposure to di-n-hexyl phthalate on the reproductive development of the male rat. Reprod Toxicol 28(4):468-476.
*Category References
US National Library of Medicine. Hazardous Substances Data Bank.