Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
dihydroxy-DDE
CAS # n/a
Alternative Names
2,2-bis(4-hydroxyphenyl)-1,1-dichloroethene
2,2-bis(4-hydroxyphenyl)-1,1-dichloroethylene
Category*
Metabolite/Degradate
Evidence Supporting This Chemical as an Endocrine Disruptor
Gaido KW, Maness SC, McDonnell DP, Dehal SS, Kupfer D, Safe S. 2000. Interaction of methoxychlor and related compounds with estrogen receptor [alpha] and [beta], and androgen receptor: structure-activity studies. Mol Pharmacol 58(4):852-858.
*Category References
Glustrom LW, Mitton-Fry R.M., Wuttke D.S. 2002. Re: 1,1-Dichloro-2,2-bis-(p-chlorophenyl)ethylene and Polychlorinated Biphenyls and Breast Cancer: Combined Analysis of Five U.S. Studies. J Natl Cancer Inst 94(17):1337-1338.
Hay AG, Focht DD. 1998. Cometabolism of 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene by Pseudomonas acidovorans M3GY grown on biphenyl. Appl Environ Microbiol 64(6):2141-2146.