Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
dihydroxymethoxychlor olefin
CAS # 5180-04-1 / 14868-03-2
Alternative Names
4,4'-(2,2- dichloroethenylidene)bis-phenol
4-[2,2-dichloro-1-(4-hydroxyphenyl)ethenyl]phenol
4-[2,2-dichloro-1-(4-hydroxyphenyl)vinyl]phenol
bis(4- hydroxyphenyl)-2,2-dichloroethylene
4,4'-(2,2-dichloroethene-1,1-diyl)diphenol
Category*
Medical/Veterinary/Research
Evidence Supporting This Chemical as an Endocrine Disruptor
Blair RM, Fang H, Branham WS, Hass BS, Dial SL, Moland CL, Tong W, Shi L, Perkins R, Sheehan DM. 2000. The estrogen receptor relative binding affinities of 188 natural and xenochemicals: structural diversity of ligands. Toxicol Sci 54(1):138-153.
*Category References
Li H, Ung CY, Yap CW, Xue Y, Li ZR, Chen YZ. 2006. Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. J Mol Graph Model 25(3):313-323 (supplemental material).