Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
2,2',3,4',5',6-hexachlorobiphenyl
CAS # 38380-04-0
Alternative Name
PCB-149
Category*
Industrial additive
Evidence Supporting This Chemical as an Endocrine Disruptor
Li MH, Hsu PC, Guo YL. 2001. Hepatic enzyme induction and acute endocrine effects of 2,2 ',3,3 ',4,6 '-hexachlorobiphenyl and 2,2,3,4 ',5 ',6-hexachlorobiphenyl in prepubertal female rats. Arch Environ Contam Toxicol 41(3):381-385.
Pessah, I. N., L. G. Hansen, T. E. Albertson, C. E. Garner, T. A. Ta, Z. Do, K. H. Kim and P. W. Wong (2006). "Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1)." Chem Res Toxicol 19(1): 92-101.
*Category References
CDPH. 1988. Polychlorinated Biphenyls (PCBs). Fact Sheet.
UNEP. 1999. Guidlines for the Identification of PCBs and Materials Containing PCBs.
US EPA. 2012. Aroclor and other PCB mixtures.