Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
dimethylformamide
CAS # 68-12-2
Alternative Names
N,N-dimethylformamide
DMFA
DMF
Categories*
Byproduct/Intermediate/Reactant
Household product ingredient
Industrial additive
Medical/Veterinary/Research
Metal/Metallurgy
Pesticide ingredient
Plastic/Rubber
Solvent
Evidence Supporting This Chemical as an Endocrine Disruptor
Kassotis CD, Klemp KC, Vu DC, Lin CH, Meng CX, Besch-Williford CL, Pinatti L, Zoeller RT, Drobnis EZ, Balise VD, et al. 2015 in press. Endocrine-disrupting activity of hydraulic fracturing chemicals and adverse health outcomes after prenatal exposure in male mice. Endocrinology:en20151375.
Kassotis CD, Tillitt DE, Davis JW, Hormann AM, Nagel SC. 2014. Estrogen and androgen receptor activities of hydraulic fracturing chemicals and surface and ground water in a drilling-dense region. Endocrinology 155(3):897-907.
Ren L, Meldahl A, Lech JJ. 1996. Dimethyl formamide (DMFA) and ethylene glycol (EG) are estrogenic in rainbow trout. Chem Biol Interact 102(1):63-67.
*Category References
Kim KH, Pandey SK, Kim YH, Sohn JR, Oh JM. 2015. Emissions of amides (N,N-dimethylformamide and formamide) and other obnoxious volatile organic compounds from different mattress textile products. Ecotoxicol Environ Saf 114:350-356.
US National Library of Medicine. Haz-Map.
US National Library of Medicine. Hazardous Substances Data Bank.