Endocrine Disruption

TEDX List of Potential Endocrine Disruptors

epoxiconazole

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CAS # 133855-98-8 / 135319-73-2 (epoxiconazol) / 106325-08-0 (formerly )

Alternative Name

epoxiconazol

Category*
Pesticide ingredient

Evidence Supporting This Chemical as an Endocrine Disruptor

Grote K, Niemann L, Selzsam B, Haider W, Gericke C, Herzler M, Chahoud I. 2008. Epoxiconazole causes changes in testicular histology and sperm production in the Japanese quail (Coturnix coturnix japonica). Environ Toxicol Chem 27(11):2368-2374.

Taxvig C, Hass U, Axelstad M, Dalgaard M, Boberg J, Andeasen HR, Vinggaard AM. 2007. Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole. Toxicol Sci 100(2):464-473.

Taxvig C, Vinggaard AM, Hass U, Axelstad M, Metzdorff S, Nellemann C. 2008. Endocrine-disrupting properties in vivo of widely used azole fungicides. Int J Androl 31(2):170-176.

Trosken ER, Adamska M, Arand M, Zarn JA, Patten C, Volkel W, Lutz WK. 2006. Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. Toxicology 228(1):24-32.

Trösken ER, Scholz K, Lutz RW, Völkel W, Zarn JA, Lutz WK. 2004. Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans. Endocr Res 30(3):387-394.

*Category References

Compendium of Pesticide Common Names (CPCN).

US EPA. InertFinder.

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