Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
fenhexamid
CAS # 126833-17-8
Category*
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Kugathas S, Audouze K, Ermler S, Orton F, Rosivatz E, Scholze M, Kortenkamp A. 2015 (in press). Effects of common pesticides on prostaglandin D2 (PGD2) inhibition in SC5 mouse Sertoli cells, evidence of binding at the COX2 active site, and implications for endocrine disruption. Environ Health Perspect.
Orton F, Rosivatz E, Scholze M, Kortenkamp A. 2011. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect 119(6):794-800.
Teng Y, Manavalan TT, Hu C, Medjakovic S, Jungbauer A, Klinge CM. 2013. Endocrine disruptors fludioxonil and fenhexamid stimulate miR-21 expression in breast cancer cells. Toxicol Sci 131(1):71-83.
*Category References
Compendium of Pesticide Common Names (CPCN).
US National Library of Medicine. Haz-Map.