Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
fenvalerate
CAS # 51630-58-1
Alternative Name
cyano(3-phenoxyphenyl)methyl 4-chloro-α-(1-methylethyl)benzeneacetate
Categories*
Medical/Veterinary/Research
Pesticide ingredient
Evidence Supporting This Chemical as an Endocrine Disruptor
Du G, Shen O, Sun H, Fei J, Lu C, Song L, Xia Y, Wang S, Wang X. 2010. Assessing hormone receptor activities of pyrethroid insecticides and their metabolites in reporter gene assays. Toxicol Sci 116(1):58-66.
Eil C, Nisula BC. 1990. The binding properties of pyrethroids to human skin fibroblast androgen receptors and to sex hormone binding globulin. J Steroid Biochem 35(3/4):409-414.
Garey J, Wolff MS. 1998. Estrogenic and antiprogestagenic activities of pyrethroid insecticides. Biochemical & Biophysical Research Communications 251(3):855-859.
Go V, Garey J, Wolff MS, Pogo BGT. 1999. Estrogenic potential of certain pyrethroid compounds in the MCF-7 human breast carcinoma cell line. Environ Health Perspect 107(3):173-177.
Kojima H, Katsura E, Takeuchi S, Niiyama K, Kobayashi K. 2004. Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Environ Health Perspect 112(5):524-531.
*Category References
Compendium of Pesticide Common Names (CPCN).
US EPA. 2008. Fenvalerate-Product Cancellation Order. Federal Register 73(132):39294-39296.
US National Library of Medicine. Hazardous Substances Data Bank.