Endocrine Disruption
TEDX List of Potential Endocrine Disruptors
hexachlorobenzene
CAS # 118-74-1
Alternative Names
HCB
perchlorobenzene
Categories*
Byproduct/Intermediate/Reactant
Industrial additive
Pesticide ingredient
Plastic/Rubber
Evidence Supporting This Chemical as an Endocrine Disruptor
Smith AG, Dinsdale D, Cabral JRP, Wright AL. 1987. Goiter and wasting induced in hamsters by hexachlorobenzene. Arch Toxicol 60(5):343-349.
Van den Berg KJ, van Raaij JAGM, Bragt PC, Notten WRF. 1991. Interactions of halogenated industrial chemicals with transthyretin and effects on thyroid hormone levels in vivo. Arch Toxicol 65(1):15-19.
Visser TJ, Kaptein E, van Toor H, van Raaij JAGM, van den Berg KJ, Joe CTT, van Engelen JGM, Brouwer A. 1993. Glucuronidation of thyroid hormone in rat liver: Effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions. Endocrinology 133(5):2177-2186.
*Category References
Compendium of Pesticide Common Names (CPCN).
US National Library of Medicine. Haz-Map.